Ann worked as an epidemiologist at the Institute of Public Health (Sciensano), Belgium, before joining the University of Antwerp in 2010 and the Belgian Antibiotic Coordination Committee (BAPCOC) in 2014. She has contributed to multiple European projects on antimicrobial consumption, including ESAC (now ESAC-Net) and a collaboration with the WHO Regional Office for Europe, which later integrated its data and methods into the WHO AMC network. She has built extensive expertise on antimicrobial consumption using different antimicrobial use metrics, investigating their validity in terms of quality indicators and their clinical importance. Since 2014, she has been coordinating the Global-PPS, a standardized cross-sectional methodology integrated with a freely accessible web-based application for data entry, validation, and feedback reporting. Designed to monitor and benchmark antimicrobial use and HAI prevalence across diverse healthcare settings worldwide, it features a user-friendly interface that facilitates data-driven local implementation of AMS. The platform has proven to be a valuable tool for stakeholder education and engagement. Dedicated to sustainable and reproducible epidemiological research, she aims to generate robust scientific evidence that empowers health professionals and policymakers to optimize antibiotic use.