Over the next two decades, breast cancer incidence and mortality will double across the globe. The negative impact on women residing in Africa will be profound if effective and affordable approaches to early diagnosis and treatment are not rapidly employed and brought to scale. Breast cancer remains a scientific challenge. There is need to build scientific capacity with local and relevant clinical research. However, it is also essential to develop strategies to put what we already know into practice, promoting novel interventions and technology that can advance breast cancer control. This session will discuss strategies to allow for more women to benefit from effective, simple, and affordable technologies or interventions. A panel of researchers and clinicians working on solving some of the current challenges will debate how to accelerate the translation of research studies in the region to public health programs. Each one will be speaking from their experience, about gaps in knowledge, innovation in care delivery, training solutions and the role of advocacy.